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Greenase Biosynthesis Ltd.(Xiamen)
Address: Biomedical Bay B1-501, Wengjiao West Road, Haichang, Xiamen, China
Tel: +86(592) 6660909/6661919
Email: reception@greenase.com
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Location >> All Product >> R&D center >> Dr. Ruming Chen >> Dr. Ruming Chen (PhD, Cambridge, 2004) |
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Dr. Ruming Chen (PhD, Cambridge, 2004) |
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Ruming Chen
PhD, Cambridge 2004
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Education E
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1999.10-2004.5
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Postgraduate Student in Biological Science
PhD thesis:Proteomic Study of Mitochondrial Proteins
Supervisor:Professor Sir John E. Walker, FRS, FMedSci
Department:School of Biological Science, Cambridge University
Laboratory:Medical Research Council Mitochondrial Biology Unit
College Membership:St Edmund’s College
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1989.8-1993.6
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Undergraduate Student in Food Science
Thesis:Preparation of Peptides from Soybean Proteolysis
Supervisor:Professor Pingfan Rao
Department:Department of Biological Science and Engineering, Fuzhou University
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Employment
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2015.4-present
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Founder Chairman, CEO, CTO
Greenase Biosynthesis Ltd. (Xiamen, China)
Gene engineering, Heterologous Expression of Recombinant Proteins, Biosynthesis of Organic Molecules.
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2010.5-2015.10
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Research Associate
Cambridge Institute of Medical Research (CIMR)/Institute of Metabolic Science, Cambridge University
Crystal Structures of Key Proteins involved in Cellular Protein Synthesis
With Professor David Ron, FRS, FMedSci
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2011.7-Present
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Adjunct Professor
School of Life Science, Harbin Institute of Technology
Structural and Functional Studies of Membrane Protein Complexes in Mitochondria and Endoplasmic Reticulum
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2007.3-2010.5
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Investigative Scientist
Proteomic Studies of Mitochondrial ATP Synthase and Complex I
With Professor Sir John E. Walker, FRS, FMedSci
Medical Research Council Mitochondrial Biology Unit (MRC-MBU)
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2004.6-2007.2
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Career Development Fellow
Mass Spectrometric Analysis of Mitochondrial Membrane Proteins and their Post-translational Modification
With Professor Sir John E. Walker, FRS, FMedSci
Medical Research Council Mitochondrial Biology Unit (MRC-MBU)
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1993.9-1999.9
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Research Assistant
Purifcation, Analysis and Characterization of Proteins
With Professor Pingfan Rao
Institute of Biotechnology, Fuzhou University
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Publications
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1. Chen R, Rato C, Yan Y, Crespillo-Casado A, Clarke HJ, Harding HP, Marciniak SJ, Read RJ, Ron D. (2014) G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases. Elife/eLife.04871.
2. Chen R, Yan Y, Preissler S, Rato C, Ding S, Fearnley IM, Read RJ, Ron D. (2015, draft) Crystal Structure of AMPylated BiP at 1.86 Å.
3. Preissler S, Rato C, Chen R, Antrobus R, Ding S, Fearnley IM, Ron D. (2015, submitted) AMPylation matches BiP activity to client protein load to prevent over‐chaperoning of the endoplasmic reticulum. Elife.
4. Chen R, Runswick MJ, Carroll J, Fearnley IM, Walker JE. (2007) Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria. FEBS Lett. 581(17):3145-8.
5. Chen R, Fearnley IM, Peak-Chew SY, Walker JE. (2004) The phosphorylation of subunits of complex I from bovine heart mitochondria. J Biol Chem. 279:26036-45
6. Chen R, Fearnley IM, Palmer DN, Walker JE. (2004) Lysine 43 is trimethylated in subunit C from bovine mitochondrial ATP synthase and in storage bodies associated with batten disease. J Biol Chem. 279(21):21883-7
7. Chen R. (Patent) Biosynthesis of Bioactive Peptides by Gene engineering.
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Awards
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2004-2007
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Medical Research Council Career Development Fellowship
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1999-2003
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Overseas Research Studentship (ORS), the Secretary of State for Education and Science
Cambridge Trust Scholarship
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